Several critical stack-based buffer overflow vulnerabilities have been identified in the MFER parsing functionality of The Biosig Project's libbiosig version 3.9.1. These vulnerabilities, tracked as CVE-2025-66044, CVE-2025-66045, CVE-2025-66046, CVE-2025-66047, and CVE-2025-66048, allow remote attackers to execute arbitrary code by supplying specially crafted MFER files. The vulnerabilities are present in the sopen_extended function, which is responsible for parsing various medical signal data formats, and can be triggered when specific MFER tags are processed. All vulnerabilities have been assigned a CVSS 3.1 base score of 9.8 (critical), and exploitation does not require authentication or user interaction.
libbiosig is widely used in scientific and medical software, including Octave, Matlab, and sigviewer, for processing biomedical signal data such as EKG and EEG. The vulnerabilities were disclosed by Cisco Talos, which confirmed that version 3.9.1 is affected. Attackers exploiting these flaws could compromise systems that process untrusted MFER files, potentially impacting healthcare and research environments that rely on this library. Organizations using libbiosig are strongly advised to review the affected versions and apply any available patches or mitigations immediately.

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CVE entries including CVE-2025-66044, CVE-2025-66045, CVE-2025-66046, CVE-2025-66047, and CVE-2025-66048 were published, documenting critical remote code execution risks in libbiosig's MFER parser. Several entries identified specific trigger conditions such as crafted tags and advised users to update and avoid processing untrusted MFER files.
Cisco Talos disclosed multiple critical stack-based buffer overflow vulnerabilities in The Biosig Project's libbiosig MFER parsing functionality, affecting version 3.9.1. The disclosure said the bugs were caused by improper handling of MFER length fields and noted public proof-of-concept exploit availability for some issues.
The Biosig Project released a patch for multiple stack-based buffer overflow vulnerabilities in libbiosig 3.9.1 affecting MFER parsing. The flaws, later assigned CVE-2025-66043 through CVE-2025-66048, could allow remote arbitrary code execution via crafted MFER files.
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